Patients with cancer who smoke cigarettes experience more treatment failures and complications and are less likely to survive cancer than patients who stop smoking or have never smoked. Although a cancer diagnosis can be a catalyst for addressing smoking, 12.7% of patients with cancer continue to smoke cigarettes, in part because standard tobacco treatment may not effectively address the psychological distress and/or emotion dysregulation that makes quitting smoking difficult for many patients with cancer. Novel behavioral interventions are critically needed. Dialectical Behavior Therapy – Skills Training (DBT-ST) has demonstrated efficacy as a brief intervention for managing emotions and stress across varied populations, but has not been adapted for patients with cancer who smoke. To determine its suitability for this population, we conducted a scoping review of brief DBT-ST with similar populations: people with substance use, breast cancer, or emotion dysregulation. We followed PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews) guidelines. Studies were restricted to English-language publications of DBT-ST as a brief intervention of 20 or fewer sessions. We found 26 publications representing 23 research studies, extracted study details, and narratively synthesized the results. The 23 studies included 12 quasi-experimental designs, seven pilot randomized controlled trials (RCTs), and four RCTs. Studies were conducted in Iran (11), the United States (9), Australia (2), and Canada (1). All studies found at least one improvement in a main outcome following DBT-ST intervention, with results maintained at follow-up. Qualitative outcomes indicated high satisfaction with DBT-ST and good retention. Studies recruited diverse participants, with some far exceeding population averages. Over half of studies were single-gender, including only females or males. Study populations were relatively young, with only four studies including people older than 50 years. We found considerable heterogeneity across studies in intervention design, testing, and measurement. Despite concerns regarding generalizability to an older, male population with cancer who smokes, we concluded that DBT-ST as a brief intervention for people with substance use, cancer, or emotion dysregulation demonstrates sufficient positive outcomes to adapt this approach for our target patient population.