[Skip to Content]

F24 - Methods for Precise Oncology Interventions in Nutrition and Training (OnPOINT) Trial: A Lifestyle Complexity Stratification Model for Cancer Survivors

Time: 11:00 AM - 11:50 AM
Topics: Cancer, Digital Health
Poster Number: F24
Lifestyle behaviors, such as maintaining a healthy diet and engaging in regular physical activity, can reduce the risk of cancer recurrence and mitigate comorbid conditions among cancer survivors. However, individual needs for nutrition and exercise programs may vary based on medical, environmental, and psychosocial factors. To date, few studies have focused on evaluating a clinical decision-making framework that enables risk stratification to generate tailored referrals for nutrition and exercise programs, addressing the distinct needs of cancer survivors. The purpose of the OnPOINT trial is to evaluate the feasibility, acceptability, and retention of a stratified nutrition and exercise referral programs for cancer survivors, while also developing, assessing, and refining the complexity stratification model. The OnPOINT study is a two-arm randomized controlled trial that aims to enroll 300 breast, prostate, and colorectal cancer survivors who are at least six months post-treatment for their primary cancer. Eligibility criteria include: 1) age >18 years; 2) <5 servings of vegetables and fruits daily; and 3) <150 minutes of moderate-to-vigorous physical activity weekly. Eligible participants are randomized into either an 8-week virtual intervention or control arm. The 8-week virtual intervention is tailored to the unique needs of cancer survivors through a complexity stratification algorithm, which assigns participants to low, moderate, or high complexity nutrition and exercise programs. This complexity stratification algorithm integrates a range of demographic, medical, physical, environmental, and psychosocial factors, informed from clinical data obtained via EPIC electronic health records and patient-reported data from questionnaires. Enrollment commenced in September 2024. To date, 42 cancer survivors have been screened, with 6 currently enrolled in the study. The average age of those enrolled is 58 years, and the majority are non-Hispanic female breast cancer survivors. Full accrual is anticipated by Summer 2025. There is a need for nutrition and exercise programs that enable clinical providers to offer tailored referrals for cancer survivors. The OnPOINT study aims to evaluate the feasibility of implementing a complexity stratification model in clinical settings to improve nutrition and exercise referrals, with the goal of evaluating sustainable and impactful lifestyle programs for cancer survivors.
Keywords: Cancer survivorship, Health behaviors

Authors and Affliiates

Presenter: Harleen Kaur, Ph.D., University of Miami, Division of Medical Oncology, Miller School of Medicine, Sylvester Comprehensive Cancer Center
Co-Author: Paola Rossi, MD, University of Miami, Division of Medical Oncology, Miller School of Medicine, Sylvester Comprehensive Cancer Center
Co-Author: S. Grey Freylersythe, BS, University of Miami, Division of Medical Oncology, Miller School of Medicine, Sylvester Comprehensive Cancer Center
Co-Author: Warda Chaudhary, MPH, University of Miami, Division of Medical Oncology, Miller School of Medicine, Sylvester Comprehensive Cancer Center
Co-Author: Mary Martos, MD, University of Miami, Division of Medical Oncology, Miller School of Medicine, Sylvester Comprehensive Cancer Center
Co-Author: Frank J. Penedo, PhD, FSBM, University of Miami, Division of Medical Oncology, Miller School of Medicine, Sylvester Comprehensive Cancer Center
Co-Author: Jessica MacIntyre, ARNP, NP-C, AOCNP, University of Miami, Division of Medical Oncology, Miller School of Medicine, Sylvester Comprehensive Cancer Center
Co-Author: Sanoj Punnen, MD, University of Miami, Division of Medical Oncology, Miller School of Medicine, Sylvester Comprehensive Cancer Center
Co-Author: Carmen Calfa, MD, University of Miami, Division of Medical Oncology, Miller School of Medicine, Sylvester Comprehensive Cancer Center
Co-Author: Agustin Pimentel, MD, University of Miami, Division of Medical Oncology, Miller School of Medicine, Sylvester Comprehensive Cancer Center
Co-Author: Luanne Force, MD, University of Miami, Division of Medical Oncology, Miller School of Medicine, Sylvester Comprehensive Cancer Center
Co-Author: Hong Su An, PhD, University of Michigan
Chair: Tracy E. Crane, PhD, RDN, University of Miami, Division of Medical Oncology, Miller School of Medicine, Sylvester Comprehensive Cancer Center

F24 - Methods for Precise Oncology Interventions in Nutrition and Training (OnPOINT) Trial: A Lifestyle Complexity Stratification Model for Cancer Survivors

Category

Scientific > Rapid Communication Poster